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Summary Statistics

You can filter the data below or go straight to the results. Descriptions of the various cell types we distribute, such as CPLs and LCLs, can be found here. Information on ordering biomaterials can be found here.

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Disease Distributions

Subjects are grouped into distributions according to the way they were ascertained for their respective studies. This should not be confused with clinical diagnoses. Subjects in the Nicotine Dependence distribution, for example, may or may not be diagnosed with Nicotine Dependence. By default, all distributions are used.

Clinical Diagnoses

The definition of "Affected" depends on the study. The definition for the primary phenotype of each study is shown in the study breakdown section below unless hidden via the option above.

Dependence

Alcohol Dependence:

Cannabis Dependence:

Cocaine Dependence:

Nicotine Dependence:

Opioid Dependence:

Sedative Dependence:

Stimulant Dependence:

Other Dependence:

Abuse

Alcohol Abuse:

Cannabis Abuse:

Cocaine Abuse:

Opioid Abuse:

Sedative Abuse:

Stimulant Abuse:

Other Abuse:

Multiple Diagnosis Logic*: OR AND

*Example: when OR is selected, if you select both Nicotine and Alcohol dependence you get statistics for the combined set Nicotine-dependent subjects and Alcohol-dependent subjects. When AND is selected, you get statistics for subjects that are both Nicotine-dependent and Alcohol-dependent.

Demographics, Biomaterials and Clinical Instruments

Sex:

Age:Between and

Self-Identified Race/Ethnicity:

Has DNA:

Cell Types:

Cell Types Logic: OR AND

Cell type descriptions can be found here.

Clinical Instrument(s):

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Results

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Breakdown by Disease Distribution

Cell type descriptions (LCLs, CPLs, etc) can be found here.

Distribution Subjects With DNA Plasma LCLs CPLs Whole Blood
Cocaine Dependence 2,443 1,568 (64%) 95 ( 4%) 1,155 (47%) 1,485 (61%) 133 ( 5%)
Total 2,443 1,568 (64%) 95 ( 4%) 1,155 (47%) 1,485 (61%) 133 ( 5%)

Demographics, DNA and Clinical Instruments

Item Value
Subjects 2,443
With DNA 1,568 (64%)
Instrument: DSM-IV 1,340 (55%)
Instrument: Unknown 1,103 (45%)
Females / Males / Unknown 1,163 (48%) / 1,280 (52%) / 0 (0%)
Age Average: 39.9, Min: 19, Max: 63

Self-Identified Race/Ethnicity

Race/Ethnicity Subjects
African-American 1,341 (55%)
White Non-Hispanic 1,017 (42%)
Other 46 ( 2%)
White Hispanic 17 ( 1%)
Asian 13 ( 1%)
Missing 6 ( 0%)
American Indian 3 ( 0%)

Cell Types

Cell type descriptions (LCLs, CPLs, etc) can be found here.

Cell Type Subjects
LCL 1,155 (47%)
CPL 1,485 (61%)
LCL gDNA 1,141 (47%)
WB gDNA 464 (19%)
Plasma 95 ( 4%)
Whole Blood 133 ( 5%)

Diagnoses

Disease Affected* Unaffected Other
Alcohol Dependence 801 (33%) 656 (27%) 986 (40%)
Cannabis Dependence 505 (21%) 839 (34%) 1,099 (45%)
Cocaine Dependence 1,291 (53%) 298 (12%) 854 (35%)
Nicotine Dependence 747 (31%) 514 (21%) 1,182 (48%)
Opioid Dependence 469 (19%) 979 (40%) 995 (41%)
Other Drug Dependence 207 ( 8%) 929 (38%) 1,307 (53%)
Sedative Dependence 119 ( 5%) 1,053 (43%) 1,271 (52%)
Stimulant Dependence 210 ( 9%) 943 (39%) 1,290 (53%)
Alcohol Abuse 118 ( 5%) 244 (10%) 2,081 (85%)
Cannabis Abuse 126 ( 5%) 259 (11%) 2,058 (84%)
Cocaine Abuse 0 ( 0%) 250 (10%) 2,193 (90%)
Opioid Abuse 73 ( 3%) 263 (11%) 2,107 (86%)
Other Drug Abuse 14 ( 1%) 253 (10%) 2,176 (89%)
Sedative Abuse 35 ( 1%) 272 (11%) 2,136 (87%)
Stimulant Abuse 17 ( 1%) 261 (11%) 2,165 (89%)

*The definition of affected depends on the study and is shown in the study breakdown below (unless hidden via the option above).

Breakdown by NIDA Studies

Cell type descriptions (LCLs, CPLs, etc) can be found here. The "Definition of Affected" refers to the primary phenotype of the study.

Cocaine Dependence
Study Name PI Definition of Affected N With DNA Plasma LCLs CPLs Whole Blood
7 An Introduction to the Family Study of Cocaine Laura Bierut DSM Cocaine Dependence 1,914 1,049 (55%) 95 ( 5%) 852 (45%) 990 (52%) 103 ( 5%)
13 Genetics of Cocaine Induced Psychosis Joseph F. Cubells DSM Cocaine Dependence 249 241 (97%) 0 ( 0%) 239 (96%) 224 (90%) 1 ( 0%)
29 Genetics Protocol of the Cocaine Use Reduction with Buprenorphine (CURB) Study; CTN-0048 David A. Nielsen DSM Cocaine Dependence 280 278 (99%) 0 ( 0%) 64 (23%) 271 (97%) 29 (10%)
Total 2,443 1,568 (64%) 95 ( 4%) 1,155 (47%) 1,485 (61%) 133 ( 5%)

cell_file version: 2023-11-14 #2